{"id":1272,"date":"2023-07-05T17:00:35","date_gmt":"2023-07-05T17:00:35","guid":{"rendered":"https:\/\/innotech.uz\/?page_id=1272"},"modified":"2023-08-05T10:58:16","modified_gmt":"2023-08-05T10:58:16","slug":"simpatil","status":"publish","type":"page","link":"https:\/\/innotech.uz\/uz\/simpatil\/","title":{"rendered":"\u0421\u0438\u043c\u043f\u0430\u0442\u0438\u043b"},"content":{"rendered":"
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TIBBIYOTDA QO\u2019LLANILISHIGA DOIR YO\u2019RIQNOMA
\nSIMPATIL\n<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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Preparatning savdo nomi<\/strong>: Simpatil<\/p>

Chiqarilish shakli:<\/strong> plyonka qobiq bilan qoplangan tabletkalar.<\/p>

Tarkibi<\/strong>:<\/p>

1 tabletka quyidagilarni saqlaydi:<\/p>

faol moddalar: <\/em><\/p>

Eshsholsiyaning quruq ekstrakti \u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 20,0 mg<\/p>

Do\u2019lananing quruq ekstrakti \u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 75,0 mg<\/p>

Magniy oksidi \u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 124,35 mg bu 75,0 mg elementar magniyga ekvivalent<\/p>

yordamchi moddalar:<\/em> mikrokristall sellyuloza \u2013 122,0 mg; natriy karboksimetilkraxmali \u2013 15,0 mg; mikronlangan stearin kislotasi \u2013 3,65 mg<\/p>

plyonka qobiqning tarkibi:<\/em><\/p>

Himoyalovchi glazuri 2,0 mg; gummilak \u2013 1,554 mg, povidon \u2013 0,223 mg, glitserol monoatsetati \u2013 0,223 mg;<\/p>

Bo\u2019yalgan kukun 13,0 mg: gipromelloza \u2013 7,150 mg, titan dioksidi (E171) \u2013 3,704 mg, makrogol 6000 \u2013 1,788 mg, indigokarmin (E 132) \u2013 0,344 mg, azorubin (E 122) \u2013 0,013 mg, temir II oksidi (E 172) \u2013 0,001 mg, talk juda oz miqdorda.<\/p>

Ta\u2019rifi:<\/strong> dumaloq shaklli, ikki tomoni qavariq, moviy rangli qobiq bilan qoplangan tabletkalar. Farmakoterapevtik guruhi: <\/strong>sedativ vosita.<\/p>

ATX kodi<\/strong>: N05CM<\/p>

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Farmakologik xususiyatlari <\/strong><\/p>

Preparat sedativ ta\u2019sir ko\u2019rsatadi, xavotirlik xolati va u bilan bog\u2019liq bo\u2019lgan vegetativ buzilishlar, taxikardiya va uyquning buzilishlarini bartaraf qiladi. Do\u2019lana ekstraktidagi biologik faol moddlar \u2013 uchterpen birikmalari va flavonoidlar spazmolitik ta\u2019sir ko\u2019rsatadi, yurak va miya tomirlarini tanlab kengaytirib, markaziy nerv tizimi va miokardning qo\u2019zg\u2019aluvchanligini pasaytiradi. Eshsholsiya ekstrakti anksiolitik, sedativ ta\u2019sir ko\u2019rsatadi, uyquga ketish vaqtini qisqartiradi va dissomniyaning yengil shakllarida uyquning sifatini yaxshilaydi. Eshsholsiya alkoloidlarining protopin guruh in vitro gamma-aminomoy kislotasini miyaning unga sezgir bo\u2019lgan retseptorlari bilan bog\u2019lanishni oshiradi.<\/p>

Magniy natriy va kaliy ionlarining membranalar orqali almashinuvining boshqarilishini yaxshilaydi, kalsiy ionlarining antagonisti hisoblanadi, neyromushak sinapslar bo\u2019ylab qo\u2019zg\u2019aluvchanlikni o\u2019tishi, silliq va ko\u2019ndalang targ\u2019il mushaklarning qisqarish qobiyatini pasaytiradi; shuningdek neyrosedativ, spazmolitik va anksiolitik ta\u2019sir ko\u2019rsatdi. Farmakokinetikasi<\/em><\/strong><\/p>

Me\u2019dada magniy oksidi magniy xloridiga aylanadi, va ingichka ichakda passiv so\u2019rilish mexanizmi yordamida so\u2019riladi, so\u2019rilish darajasi 50% dan oshmaydi. Magniy asosan siydik bilan chiqariladi. Komponentlarining ta\u2019siri kinetik kuzatishlar uchun murakkabdir.<\/p>

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Qo\u2019llanilishi <\/strong><\/p>

— yuqori ko\u2019zg\u2019aluvchanlik, bezovtalik, yuqori ta\u2019sirchanlik, xavotirlik, qo\u2019rquv, kuchli toliqish, yurak urishi bilan kechuvchi emotsional zo\u2019riqish va stress holatlari;<\/p>

— uyquni buzilishi (yengil shakli).<\/p>

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Qo\u2019llash usuli va dozalari <\/strong><\/p>

Ichga qabul qilish uchun.<\/p>

2 tabletkadan kuniga 2 marta (ertalab va kechqurun) ovqatdan oldin, suv bilan qabul qilinadi. Davolashning davomiyligi 3-4 hafta. Davolash kurslari orasidagi interval 3 hafta.<\/p>

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Nojo\u2019ya ta\u2019sirlari<\/strong><\/p>

Me\u2019da-ichak yo\u2019llari tomonidan: diareya, epigastral sohada og\u2019riq kuzatilishi mumkin. Agar yo\u2019riqnomada ko\u2019rsatilgan nojo\u2019ya samaralaridan birortasi og\u2019irlashsa yoki Siz yo\u2019riqnomada ko\u2019rsatilmagan har qanday boshqa nojo\u2019ya samaralarni sezsangiz, bu haqida shifokorga xabar bering.<\/p>

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Qo\u2019llash mumkin bo\u2019lmagan holatlar<\/strong><\/p>

Preparatning komponentlariga yuqori sezuvchanlik, og\u2019ir buyrak yetishmovchiligi (kreatinin klirensi 30 ml\/min dan past), 18 yoshgacha bo\u2019lganlarda qo\u2019llash mumkin emas.<\/p>

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Dorilarning o\u2019zaro ta\u2019siri<\/strong><\/p>

Preparatni xinidin saqlovchi dori vositalari bilan birga qo\u2019llash tavsiya qilinmaydi, chunki siydikni ishqorlanishi sababli xinidinni buyraklar orqali chiqarilishi pasayadi va dozani oshirib yuborilishi rivojlanishi mumkin (qon plazmasida xinidinning konsentratsiyasini oshishi sababli).<\/p>

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Maxsus ko\u2019rsatmalar <\/strong><\/p>

Homiladorlik va emizish davrida qo\u2019llanishi <\/em><\/strong><\/p>

Homiladorlik va emizish davrida qo\u2019llash tavsiya etilmaydi.<\/p>

Transport vositalarini boshqarish qobiliyatiga ta\u2019siri<\/em><\/strong><\/p>

Davolash vaqtida diqqatni yuqori jamlashni va psixomotor reaksiyalar tezligini talab qiluvchi potensail xavfli faoliyat turlarini (transport vositalarini boshqarish, harakatlanayotgan mexanizmlar bilan ishlash va boshqa.) bajarishda ehtiyotkorlikka rioya qilish kerak.<\/p>

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Dozani oshirib yuborilishi<\/strong><\/p>

Preparatni katta dozalarda qabul qilish siydik tutilishiga olib kelishi mumkin.<\/p>

Davolash: regidratatsiya, jadallashtirilgan diurez. Buyrak yetishmovchiligi bo\u2019lgan holda gemodializ yoki peritoneal dializ o\u2019tkazish kerak.<\/p>

\u00a0<\/strong><\/p>

Chiqarilish shakli<\/strong><\/p>

Plyonka qobiq bilan qoplangan tabletkalar.<\/p>

20 tabletkadan PVX\/alyumin blisterda. 2 yoki 3 blisterdan tibbiyotda qo\u2019llanilishiga doir yo\u2019riqnomasi bilan birga karton qutida.<\/p>

\u00a0<\/strong><\/p>

Saqlash sharoiti <\/strong><\/p>

25\u00b0C dan yuqori bo\u2019lmagan haroratda saqlansin.<\/p>

Bolalar ololmaydigan joyda saqlansin.<\/p>

\u00a0<\/strong><\/p>

Yaroqlilik muddati <\/strong><\/p>

3 yil.<\/p>

O\u2019ramda ko\u2019rsatilgan muddatdan so\u2019ng ishlatilmasin.<\/p>

\u00a0<\/strong><\/p>

Dorixonalardan berish tartibi <\/strong><\/p>

Retseptsiz.<\/p>

\u00a0<\/strong><\/p>

Qayd etish guvohnomasining egasi<\/strong><\/p>

Laboratoriya Innotek Internasional, Fransiya<\/p>

22, avenyu Aristid Brian, 94110, Arkey<\/p>

\u00a0<\/strong><\/p>

\u00a0<\/strong><\/p>

Ishlab chiqaruvchi <\/strong><\/p>

Innotera SHuzi,<\/p>

Ryu Rene SHantero, SHuzi-syur-Sis,<\/p>

Valuar-syur-Sis 41150, Fransiya.<\/p>

\u00a0<\/p>

O<\/strong>\u2019<\/strong>zbekiston<\/strong> Respublikasi xududida dori vositalarining sifati bo<\/strong>\u2019<\/strong>yicha<\/strong> e<\/strong>\u2019<\/strong>tirozlar<\/strong> (takliflar) ni qabul qiluvchi tashkilotning nomi va manzili<\/strong>:<\/strong><\/p>

\u201cLaboratoriya Innotek Internasional\u201d O\u2019zbekistondagi vakolatxonasi:<\/p>

Yuridik manzili: Toshkent sh., Fidokor ko\u2019ch. 7A<\/p>

Tel.: 140-43-40; 140-43-41.<\/p>

E-mail: uz.innotech@ sks.uz<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>","protected":false},"excerpt":{"rendered":"

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